Our new variable-angle illumination microscopy extends Fourier ptychography to acquire high-resolution, large field-of-view complex polarimetric data, accounting for light's vectorial nature.
We use a SPAD array camera and deep neural network process speckle fluctuations to reconstruct deep tissue dynamics and monitor internal flow in phantoms."
A high-sensitivity DCS system using a SPAD array can detect small deep tissue perturbations, measure human pulse with high fidelity, and identify physiological changes in the prefrontal cortex.